SCHEMBL4242011

SCHEMBL4242011

CCO[Si](OCC)(c1cccc(C)c1)c1cccc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.42
IDO1 P14902 3/20 0.37
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
HPGD P15428 2/20 0.33
METAP2 P50579 1/20 0.33
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561373 0.84 ACHE (0.42) ACHEIDO1ALDH1A1MAPK1CYP1A2
SCHEMBL3482226 0.81 TACR1 (0.33) ACHEALDH1A1MAPK1MAPTTDP1
SCHEMBL29672899 0.77 ACHE (0.48) ACHEIDO1ALDH1A1MAPK1CYP1A2
SCHEMBL1562121 0.77 ACHE (0.48) ACHEIDO1ALDH1A1MAPK1CYP1A2
SCHEMBL34937 0.76 LTA4H (0.37) ALDH1A1MAPTHTTHPGDL3MBTL1
SCHEMBL3481554 0.76 LMNA (0.39) ACHEMAPTCYP2C19HTTTDP1
SCHEMBL23521414 0.74 IDO1 (0.45) IDO1ALDH1A1MAPK1MAPTTAAR1
SCHEMBL5023574 0.74 CYP3A4 (0.44) ALDH1A1CYP3A4MAPTTDP1HPGD
SCHEMBL296972 0.74 ACHE (0.38) ACHEIDO1ALDH1A1MAPTHTT
SCHEMBL712057 0.74 ESR1 (0.37) ALDH1A1MAPTHTTHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693728-B Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-116693727-B Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-116606390-B Olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2025-01-07 CN claimed
CN-116606391-B Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2024-11-19 CN claimed
CN-116693727-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-05 CN claimed
CN-116693728-A Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-09-05 CN claimed
CN-116606391-A Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2023-08-18 CN claimed
CN-116606390-A Olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-08-18 CN claimed
CN-108129591-B External electron donor composition, olefin polymerization catalyst system and application of external electron donor composition and olefin polymerization catalyst system 杨翠 2021-05-28 CN claimed
CN-116693727-B Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-116693728-B Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-116606390-B Olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2025-01-07 CN disclosed
CN-116606391-B Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2024-11-19 CN disclosed
CN-116693727-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-05 CN disclosed
CN-109280109-B Catalyst system for olefin polymerization and application thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
EP-1947123-B1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF AND CATALYST CONTAINING THE SAME CHINA PETROLEUM & CHEMICAL (CN) 2016-03-09 EP disclosed
US-20150239998-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF AND CATALYST COMPRISING THE SAME CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-08-27 US disclosed
US-20090318643-A1 Catalyst Component for Ethylene Polymerization, Preparation Thereof and Catalyst Comprising the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2009-12-24 US disclosed
US-20090005524-A1 Catalysts for ethylene polymerization, main catalyst components thereof and process for preparing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2009-01-01 US disclosed
EP-1947123-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF AND CATALYST CONTAINING THE SAME China Petroleum & Chemical Corporation (CN) 2008-07-23 EP disclosed