Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.37 |
| ▸ | PLAT | P00750 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 4/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240759 | 0.85 | HTR2C (0.38) | OPRD1OPRK1KCNH2HTR2CP2RY14 | |
| SCHEMBL4244427 | 0.85 | HTR2C (0.38) | OPRD1OPRK1KCNH2HTR2CP2RY14 | |
| SCHEMBL4240121 | 0.85 | KDM1A (0.38) | HTR2CPLATKDM1AMAOB | |
| SCHEMBL4238694 | 0.84 | CHRM1 (0.39) | CHRM2 | |
| SCHEMBL4240748 | 0.84 | HRH1 (0.35) | CHRM2KDM1A | |
| SCHEMBL4245341 | 0.81 | HTR1A (0.45) | OPRD1KCNH2HTR2CPLATHTR1A | |
| SCHEMBL4239109 | 0.75 | CCR5 (0.41) | ADAMTS7CHRM2CHRM5DRD2 | |
| SCHEMBL4240155 | 0.73 | CCR5 (0.41) | KCNH2ADAMTS7DRD1SLC6A2DRD3 | |
| SCHEMBL4243005 | 0.70 | HTR2C (0.45) | OPRD1OPRK1KCNH2HTR2CSLC6A2 | |
| SCHEMBL11606211 | 0.68 | HTR2C (0.45) | OPRD1OPRK1KCNH2HTR2CP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491735-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| US-20050277670-A1 | Chemokine receptor binding compounds | ANORMED INC. | 2005-12-15 | — | — | US | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277670-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | OPRD1 245/4885OPRK1 158/4885KCNH2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.