Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | DRD5 | P21918 | 4/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240759 | 0.91 | HTR2C (0.38) | HTR2CPLATPIM1PIM3PIM2 | |
| SCHEMBL4243013 | 0.85 | OPRD1 (0.42) | HTR2CPLATPIM1PIM3PIM2 | |
| SCHEMBL4242886 | 0.77 | CCR5 (0.36) | PTGS2KCNH2 | |
| SCHEMBL4236456 | 0.74 | GCGR (0.34) | PTGS2CHRM2KDM1ACHRM1CHRM3 | |
| SCHEMBL4240422 | 0.74 | CHRM2 (0.44) | PLATHTR1ACHRM2HTR7KDM1A | |
| SCHEMBL4240756 | 0.71 | HTR2C (0.40) | HTR2CSLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4247925 | 0.69 | CCR5 (0.36) | PTGS2KCNH2 | |
| SCHEMBL4240748 | 0.69 | HRH1 (0.35) | CHRM2KDM1ACHRM1CHRM3HRH1 | |
| SCHEMBL4245341 | 0.66 | HTR1A (0.45) | HTR2CPLATHTR1AOPRD1HTR7 | |
| SCHEMBL4597238 | 0.65 | PSEN1 (0.51) | CHRM5KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491735-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| US-20050277670-A1 | Chemokine receptor binding compounds | ANORMED INC. | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277670-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | HTR2C 2293/4885PLAT 3140/4885PIM1 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.