Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 1.00 |
| ▸ | NAMPT | P43490 | 3/20 | 0.69 |
| ▸ | JAK2 | O60674 | 1/20 | 0.65 |
| ▸ | TYK2 | P29597 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429268 | 0.85 | BCAT2 (0.73) | BCAT2NAMPTJAK2TYK2NPC1 | |
| SCHEMBL19520187 | 0.84 | LMNA (0.81) | BCAT2NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22594469 | 0.83 | EPHX1 (0.71) | BCAT2NPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL30423427 | 0.83 | BCAT2 (0.71) | BCAT2NAMPTJAK2TYK2NPC1 | |
| SCHEMBL29151224 | 0.81 | BCAT2 (0.69) | BCAT2NAMPTNPC1RAB9AMAPT | |
| SCHEMBL167081 | 0.81 | NAMPT (1.00) | BCAT2NAMPTNPC1RAB9AKCNK3 | |
| Hydrochloric Acid SCHEMBL27890956 | 0.80 | NAMPT (0.97) | BCAT2NAMPTNPC1RAB9AKCNK3 | |
| SCHEMBL19662798 | 0.80 | NT5E (0.70) | BCAT2NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL19662757 | 0.80 | BCAT2 (0.66) | BCAT2LMNAHIF1AKCNQ3KCNQ2 | |
| SCHEMBL24202631 | 0.79 | SIRT1 (0.83) | JAK2TYK2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4545517-A1 | NAV1.8 INHIBITOR | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023246867-A1 | NAV1.8 INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-12-28 | — | — | WO | disclosed |
| US-20220127265-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2022-04-28 | — | — | US | disclosed |
| EP-3334727-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES | H. Hoffnabb-La Roche Ag (CH) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017025523-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2017-02-16 | — | — | WO | disclosed |
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127265-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, HDAC1, CREBBP | BCAT2 3212/4885NAMPT 945/4885JAK2 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.