Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30423427 | 0.98 | BCAT2 (0.71) | BCAT2HTTJAK2TYK2NAMPT | |
| SCHEMBL18979446 | 0.90 | PTPN1 (0.66) | BCAT2HTTJAK2TYK2NAMPT | |
| SCHEMBL4243217 | 0.85 | BCAT2 (1.00) | BCAT2HTTJAK2TYK2NAMPT | |
| Nicotinanilide SCHEMBL352439 | 0.81 | LMNA (0.83) | HTTJAK2TYK2NAMPTNPC1 | |
| SCHEMBL27727308 | 0.81 | POLB (0.67) | BCAT2NPC1RAB9AKDM4ELMNA | |
| SCHEMBL10338266 | 0.81 | PTPN1 (0.61) | BCAT2NPC1RAB9APTPN1P4HTM | |
| Nicotinanilide SCHEMBL29067673 | 0.81 | LMNA (0.83) | HTTJAK2TYK2NAMPTNPC1 | |
| Nicotinanilide SCHEMBL8155304 | 0.80 | LMNA (0.81) | HTTJAK2TYK2NAMPTNPC1 | |
| SCHEMBL24202631 | 0.79 | SIRT1 (0.83) | HTTJAK2TYK2NPC1RAB9A | |
| N-Phenylbenzamide SCHEMBL31966 | 0.79 | SIRT1 (0.83) | HTTJAK2TYK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6032784-A | — | — | None | — | — | JP | disclosed |
| JP-2019316-A | — | — | None | — | — | JP | disclosed |
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| WO-2015157127-A1 | THERAPUETIC USES OF SELECTED PYRIMIDINE COMPOUNDS WITH ANTI-MER TYROSINE KINASE ACTIVITY | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-10-15 | — | — | WO | disclosed |
| WO-2014062938-A1 | RORY MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-2132196-A1 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | Pfizer Products Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008104869-A1 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| JP-H0632784-A | 4-ALKYL-SUBSTITUTED PYRIMIDINE-5-CARBOXANILIDES, THEIR PREPARATION, COMPOSITION CONTAINING THEM AND THEIR USE AS FUNGICIDE | HOECHST AG | 1994-02-08 | — | — | JP | disclosed |
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |
| JP-H0219316-A | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF LEUKEMIA | UNIROYAL CHEM CO INC | 1990-01-23 | — | — | JP | disclosed |
| CN-1038450-A | The 5-pyrimidine carboxamide analog derivative that replaces | UNIROYAL CHEM CO INC (US) | 1990-01-03 | — | — | CN | disclosed |