SCHEMBL4243945

SCHEMBL4243945

CC1(c2ccc(Cl)cc2)CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
KDM1A O60341 1/20 0.38
SLC6A4 P31645 3/20 0.34
SLC6A3 Q01959 3/20 0.34
CHRNA1 P02708 2/20 0.34
CHRNG P07510 2/20 0.34
CHRNB1 P11230 2/20 0.34
CHRNB2 P17787 2/20 0.34
SLC6A2 P23975 2/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRND Q07001 2/20 0.34
CCR2 P41597 2/20 0.34
DRD2 P14416 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4948662 0.83 ESR2 (0.39) CYP2D6CYP2C19
SCHEMBL6528313 0.82 MAOA (0.41) MAOAMAOBKDM1ACCR2CYP2D6
SCHEMBL231895 0.82 MAOA (0.41) MAOAMAOBKDM1ACCR2CYP2D6
SCHEMBL1720274 0.80 NPC1 (0.37) MAOAMAOBKDM1ASLC6A4SLC6A3
SCHEMBL14667575 0.80 MAOB (0.44) MAOAMAOBKDM1ASLC6A4SLC6A3
SCHEMBL1720397 0.74 SLC6A4 (0.39) KDM1ASLC6A4SLC6A3SLC6A2
SCHEMBL1733173 0.73 TAAR1 (0.35) KDM1ASLC6A4LMNACYP2D6CYP2C19
Hydrochloric Acid SCHEMBL15200596 0.68 KDM1A (0.59) MAOAMAOBKDM1ASLC6A4SLC6A3
SCHEMBL4392309 0.67 P2RX7 (0.31) HTT
SCHEMBL1733751 0.67 BACE1 (0.34) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed