Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663383 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL663382 | 0.81 | SLC6A9 (0.36) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL905936 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8597557 | 0.77 | ADORA3 (0.32) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8547909 | 0.76 | KDR (0.37) | ALDH1A1LMNAHTTL3MBTL1APP | |
| SCHEMBL7717266 | 0.74 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL30803820 | 0.74 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8936038 | 0.73 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8935948 | 0.73 | ADORA2A (0.36) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8597197 | 0.72 | ADORA3 (0.32) | ALDH1A1LMNAHTTL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068905-A2 | ALBUMIN FUSION PROTEINS | Human Genome Sciences, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008033413-A2 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. (US) | 2008-03-20 | — | — | WO | disclosed |