Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542683 | 0.84 | ALDH1A1 (0.37) | ALDH1A1ADORA3SCN9ABCHEACHE | |
| SCHEMBL663382 | 0.80 | SLC6A9 (0.36) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL4244108 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8547909 | 0.77 | KDR (0.37) | ALDH1A1LMNAHTTL3MBTL1ACHE | |
| SCHEMBL30803820 | 0.76 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL7717266 | 0.76 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8936038 | 0.75 | ADORA2A (0.37) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8935948 | 0.74 | ADORA2A (0.36) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL663383 | 0.74 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTL3MBTL1ADORA3 | |
| SCHEMBL8597197 | 0.73 | ADORA3 (0.32) | ALDH1A1LMNAHTTL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990417-A1 | ALBUMIN INSULIN FUSION PROTEIN | Human Genome Sciences, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2261250-B1 | GCSF-Albumin fusion proteins | HUMAN GENOME SCIENCES INC (US) | 2015-07-01 | — | — | EP | disclosed |
| EP-1708751-B1 | METHODS OF KILLING TUMOR CELLS BY TARGETING INTERNAL ANTIGENS EXPOSED ON APOPTOTIC TUMOR CELLS | VACCINEX INC (US) | 2011-09-28 | — | — | EP | disclosed |
| EP-2277910-A1 | Albumin fusion proteins | Human Genome Sciences, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277889-A2 | Fusion proteins of albumin and interferon beta | Human Genome Sciences, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277888-A2 | Fusion proteins of albumin and erythropoietin | Human Genome Sciences, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2261250-A1 | Albumin fusion proteins | HUMAN GENOME SCIENCES, INC. (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-1997829-A1 | Albumin fusion proteins | Human Genome Sciences, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |
| EP-1991577-A2 | MODULATION OF MDL-1 ACTIVITY FOR TREATMENT OF INFLAMMATORY DISEASE | Parkinson, John F. (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1633316-A4 | ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO TRAIL RECEPTORS | HUMAN GENOME SCIENCES INC (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2003060071-A2 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003059934-A2 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003054216-A2 | ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO TRAIL RECEPTORS | HUMAN GENOME SCIENCES, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| US-6051207-A | PHOSPHATIDYLSERINE LINKED ISOXAZOLE SULFONAMIDE DERIVATIVES; DIAGNOSING AND IMAGING CARDIOVASCULAR DISORDERS | NYCOMED IMAGING AS (NO) | 2000-04-18 | — | — | US | disclosed |
| EP-0624097-B1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1998-03-18 | — | — | EP | disclosed |
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |
| US-5677445-A | DIAGNOSIS, THERAPY | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5367080-A | PYRIDINE DERIVATIVES | STERLING WINTHROP INC. (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0624097-A1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1994-11-17 | — | — | EP | disclosed |
| WO-1992008494-A2 | TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1992-05-29 | — | — | WO | disclosed |