Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389669 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL1176985 | 0.81 | LTA4H (0.46) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL390537 | 0.81 | LTA4H (0.46) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL1176986 | 0.81 | LTA4H (0.46) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL389670 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL489877 | 0.80 | TSHR (0.40) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL392982 | 0.80 | KMT2A (0.39) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL489879 | 0.80 | TSHR (0.40) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL392983 | 0.80 | KMT2A (0.39) | ALDH1A1KMT2ALTA4HCTSKTSHR | |
| SCHEMBL490084 | 0.80 | TSHR (0.40) | ALDH1A1KMT2ALTA4HCTSKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | ALDH1A1 3119/4885KMT2A 4780/4885LTA4H 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.