Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | F12 | P00748 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | PDE6D | O43924 | 3/20 | 0.31 |
| ▸ | PDE6A | P16499 | 3/20 | 0.31 |
| ▸ | PDE6G | P18545 | 3/20 | 0.31 |
| ▸ | PDE6B | P35913 | 3/20 | 0.31 |
| ▸ | PDE6C | P51160 | 3/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 3/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425919 | 0.82 | HDAC3 (0.43) | CNR2F12HTTFAAHMGLL | |
| SCHEMBL427992 | 0.82 | F12 (0.37) | CNR2F12FAAHMGLLGAA | |
| SCHEMBL427660 | 0.76 | CNR2 (0.35) | CNR2GAAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL424701 | 0.74 | F12 (0.42) | F12FAAHMGLLGAAMGAM | |
| SCHEMBL425578 | 0.72 | FAAH (0.47) | F12HTTFAAHMGLLGAA | |
| SCHEMBL427663 | 0.70 | FAAH (0.36) | CNR2F12FAAHMGLLGAA | |
| SCHEMBL424826 | 0.70 | HCAR3 (0.49) | — | |
| SCHEMBL444875 | 0.70 | HCAR3 (0.40) | FAAHMGLLGAAMGAMAMY1A | |
| SCHEMBL7906239 | 0.69 | KCNMA1 (0.37) | CNR2FAAHMGLLGAAKDM4E | |
| SCHEMBL425937 | 0.68 | KCNMA1 (0.51) | CNR2HTTSMN1; SMN2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | CNR2 9/4885F12 785/4885PIK3CB 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.