Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Araprofen SCHEMBL670976 | 0.88 | FABP4 (0.61) | FABP4MEN1KMT2ANPC1RAB9A | |
| Araprofen SCHEMBL29711441 | 0.88 | FABP4 (0.61) | FABP4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1962523 | 0.86 | MEN1 (0.57) | FABP4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18109767 | 0.86 | FABP4 (0.85) | FABP4MEN1KMT2AAKR1C3PTGS1 | |
| SCHEMBL19586692 | 0.83 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Fenamic Acid SCHEMBL27681709 | 0.83 | FABP4 (0.85) | FABP4MEN1KMT2AAKR1C3PTGS1 | |
| SCHEMBL7841736 | 0.83 | FABP4 (0.85) | FABP4MEN1KMT2AAKR1C3PTGS1 | |
| Fenamic Acid SCHEMBL25828 | 0.82 | FABP4 (0.92) | FABP4MEN1KMT2AAKR1C3PTGS1 | |
| Fenamic Acid SCHEMBL29622832 | 0.82 | FABP4 (0.92) | FABP4MEN1KMT2AAKR1C3PTGS1 | |
| SCHEMBL7566561 | 0.82 | RAB9A (0.62) | FABP4MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | CLIC1, ASIC1, CLIC4 | FABP4 1600/4885MEN1 2715/4885KMT2A 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.