Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PGD | P52209 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630284 | 0.83 | TSHR (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL514701 | 0.80 | TSHR (0.41) | TSHRPGDCYP2C9PDE4A | |
| SCHEMBL1168152 | 0.80 | MMP1 (0.42) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9006278 | 0.77 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7118530 | 0.77 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14935874 | 0.77 | LMNA (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL3749627 | 0.77 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1468445 | 0.77 | MMP1 (0.44) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL3386669 | 0.75 | MMP1 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8624519 | 0.75 | TSHR (0.39) | TSHRPGDCYP2C9PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569408-A4 | WET POWDER FILM-FORMING COMPOSITIONS | WARNER JENKINSON COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0569408-A1 | WET POWDER FILM-FORMING COMPOSITIONS | WARNER-JENKINSON COMPANY, INC. (US) | 1993-11-18 | — | — | EP | claimed |
| WO-1992011002-A1 | WET POWDER FILM-FORMING COMPOSITIONS | WARNER-JENKINSON COMPANY (US) | 1992-07-09 | — | — | WO | claimed |
| WO-2009117227-A2 | DEPROTECTION OF OLIGONUCLEOTIDES THAT CONTAIN ONE OR MORE RIBONUCLEOTIDES | MERCK & CO., INC. (US) | 2009-09-24 | — | — | WO | disclosed |