Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168152 | 0.82 | MMP1 (0.42) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL94758 | 0.81 | MMP1 (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL23630284 | 0.80 | TSHR (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9547012 | 0.79 | TSHR (0.35) | TSHRSRCLDHASRR | |
| Cadaverine Tartrate SCHEMBL6754064 | 0.79 | TSHR (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14935874 | 0.78 | LMNA (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL3749627 | 0.78 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9006278 | 0.78 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1468445 | 0.78 | MMP1 (0.44) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1864892 | 0.78 | LMNA (0.42) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3369179-B2 | — | — | 2003-01-20 | — | — | JP | claimed |
| EP-0666901-A4 | METHOD AND COMPOSITIONS FOR REMOVING AN ALGINATE FROM A CUTANEOUS SUBSTRATE. | MERCK & CO INC (US) | 1999-11-24 | — | — | EP | claimed |
| EP-0666901-A1 | METHOD AND COMPOSITIONS FOR REMOVING AN ALGINATE FROM A CUTANEOUS SUBSTRATE | E.R. SQUIBB & SONS, INC. (US) | 1995-08-16 | — | — | EP | claimed |
| WO-1994009106-A1 | METHOD AND COMPOSITIONS FOR REMOVING AN ALGINATE FROM A CUTANEOUS SUBSTRATE | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | claimed |
| US-5443971-A | Pyranones | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| US-5292525-A | Using chelant solution | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |