Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248193 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL16513957 | 0.77 | MAPT (0.56) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL519289 | 0.77 | CTSB (0.62) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL29847859 | 0.77 | MAPT (0.56) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5945280 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL8103840 | 0.75 | ALDH1A1 (0.70) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL853018 | 0.74 | MAPT (0.60) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL939398 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL13405633 | 0.73 | MAPT (0.83) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL18396735 | 0.73 | ALDH1A1 (0.66) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137553-A1 | Thiazepine Oxazolidinones as Antibacterial Agents | PHARMACIA AND UPJOHN COMPANY LLC (US) | 2009-05-28 | — | — | US | disclosed |
| EP-1819702-A1 | THIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056875-A1 | THIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137553-A1 | Thiazepine Oxazolidinones as Antibacterial Agents | OXA1L, TBCD, CLPP | ALDH1A1 2766/4885MAPT 2991/4885POLB 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.