Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246225 | 0.82 | ALDH1A1 (0.37) | ALDH1A1NR3C1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9076404 | 0.72 | NOTUM (0.39) | ALDH1A1HPGDLMNAKDM4EEGFR | |
| SCHEMBL4244574 | 0.71 | SMN1; SMN2 (0.34) | ALDH1A1NR3C1LMNAKDM4E | |
| SCHEMBL4245180 | 0.69 | RAB9A (0.38) | ALDH1A1NR3C1LMNA | |
| SCHEMBL3436915 | 0.68 | RAB9A (0.36) | ALDH1A1NR3C1LMNA | |
| SCHEMBL4244576 | 0.64 | RAB9A (0.34) | NR3C1LMNA | |
| Ethanesulfonic Acid Amide SCHEMBL3436960 | 0.63 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL7057676 | 0.61 | MEN1 (0.32) | NR3C1MAOBMAOA | |
| SCHEMBL10961245 | 0.61 | ALKBH1 (0.41) | ALDH1A1NR3C1MCL1L3MBTL1 | |
| SCHEMBL15300802 | 0.60 | MTNR1A (0.73) | ALDH1A1LMNAKDM4EL3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | HERRMANN STEFAN | 2006-11-09 | — | — | US | disclosed |
| US-7112554-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20040176253-A1 | Substitued arylketones | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1387831-A1 | SUBSTITUTED ARYLKETONES | Bayer CropScience AG (DE) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002090336-A1 | SUBSTITUTED ARYLKETONES | BAYER CROPSCIENCE AG (DE) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | CYP1A1, CYP1A2, CYP4X1 | ALDH1A1 54/4885NR3C1 1767/4885MAOB 205/4885 |
| US-20040176253-A1 | Substitued arylketones | CYP1B1, CYP1A1, CYP2E1 | ALDH1A1 15/4885NR3C1 1113/4885MAOB 821/4885 |
| US-20090042730-A1 | Substituted Arylketones | CYP1A1, CYP1B1, CYP1A2 | ALDH1A1 37/4885NR3C1 1849/4885MAOB 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.