Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307124 | 0.79 | HMGCR (0.51) | HIF1AMEN1KMT2APOLBGAA | |
| SCHEMBL22354782 | 0.77 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL382778 | 0.77 | HPGD (0.55) | POLBGAANPSR1TSHRKCNK3 | |
| SCHEMBL1019564 | 0.76 | HPGD (0.49) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL7411650 | 0.76 | USP2 (0.50) | HIF1AUSP2TP53MEN1KMT2A | |
| SCHEMBL3282912 | 0.76 | NPC1 (0.63) | USP2TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29861033 | 0.76 | NPC1 (0.63) | USP2TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17637149 | 0.75 | HSD11B1 (0.63) | USP2TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4062484 | 0.75 | HSP90AA1 (0.63) | HIF1ATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28292159 | 0.75 | POLB (0.46) | MEN1KMT2ANPC1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |