Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958946 | 0.81 | GAA (0.52) | USP2TP53GAANPSR1HIF1A | |
| SCHEMBL6611954 | 0.79 | MAPT (0.63) | NPSR1TNFSF11TSHRPTGS1PTGS2 | |
| SCHEMBL3282912 | 0.77 | NPC1 (0.63) | USP2TP53GAAPOLBALDH1A1 | |
| SCHEMBL29861033 | 0.77 | NPC1 (0.63) | USP2TP53GAAPOLBALDH1A1 | |
| SCHEMBL17637149 | 0.77 | HSD11B1 (0.63) | USP2TP53NPSR1TSHRKDM4E | |
| SCHEMBL12950516 | 0.77 | HSP90AA1 (0.55) | USP2TP53GAANPSR1HIF1A | |
| SCHEMBL8318992 | 0.77 | ALDH1A1 (0.49) | USP2TP53GAANPSR1HIF1A | |
| SCHEMBL15680262 | 0.76 | LCK (0.61) | USP2TNFSF11TSHRPTGS1PTGS2 | |
| SCHEMBL4248920 | 0.76 | HIF1A (0.46) | USP2TP53GAANPSR1HIF1A | |
| Phenylacetic Acid SCHEMBL28250164 | 0.76 | AKR1B1 (0.55) | GAAPOLBTSHRPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | disclosed |