Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746571 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL11293043 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL11422481 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL13746541 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL11416591 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL6898586 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL11416602 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL4245354 | 0.74 | SOAT1 (0.47) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL11418961 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GLO1NPSR1 | |
| SCHEMBL7459826 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GLO1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329731-A1 | THERAPEUTIC METHODS, COMPOSITIONS, AND COMPOUNDS | NAGASAWA HERBERT T (US) | 2012-12-27 | — | — | US | disclosed |
| US-20090197865-A1 | THERAPEUTIC METHODS, COMPOSITIONS AND COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329731-A1 | THERAPEUTIC METHODS, COMPOSITIONS, AND COMPOUNDS | PC, ME3, PYGL | ALDH1A1 509/4885LMNA 2487/4885HSD17B10 1734/4885 |
| US-20090197865-A1 | THERAPEUTIC METHODS, COMPOSITIONS AND COMPOUNDS | PC, ME3, PYGL | ALDH1A1 510/4885LMNA 2309/4885HSD17B10 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.