Methacrylic Acid

Methacrylic Acid

SCHEMBL4249534

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.CCn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.36
CYP1A2 P05177 3/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.35
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
PDE4A P27815 2/20 0.33
ADORA2A P29274 2/20 0.33
PDE4B Q07343 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3635510 0.82 APEX1 (0.37) APEX1SMN1; SMN2ALDH1A1GAATYMP
Methacrylic Acid SCHEMBL1914676 0.82 APEX1 (0.37) APEX1SMN1; SMN2ALDH1A1GAATYMP
Methacrylic Acid SCHEMBL4450991 0.82 APEX1 (0.37) APEX1SMN1; SMN2ALDH1A1GAATYMP
SCHEMBL163183 0.82 MAPT (0.47) KMT2ACYP1A2MEN1MAPTPOLB
Acrylic Acid SCHEMBL4887834 0.81 LMNA (0.37) KMT2ACYP1A2MEN1MAPTPOLB
Methacrylic Acid SCHEMBL904578 0.81 APEX1 (0.33) APEX1
Methacrylic Acid SCHEMBL1008210 0.81 APEX1 (0.33) APEX1
Methacrylic Acid SCHEMBL546828 0.77 TYMP (0.41) CYP1A2LMNATSHRNFKB1BLM
Methacrylic Acid SCHEMBL634441 0.77 TYMP (0.41) CYP1A2LMNATSHRNFKB1BLM
Methacrylic Acid SCHEMBL251193 0.77 TYMP (0.41) CYP1A2LMNATSHRNFKB1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035647-B1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-10-18 EP claimed
WO-2009146067-A2 NOVEL MONOMER FOR DENTAL COMPOSITIONS UNIVERSITY OF KANSAS (US) 2009-12-03 WO claimed
WO-2009146067-A2 NOVEL MONOMER FOR DENTAL COMPOSITIONS UNIVERSITY OF KANSAS (US) 2009-12-03 WO disclosed