Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249687 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4923119 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2KMT2AHPGDKDM4E | |
| SCHEMBL23091735 | 0.83 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2KMT2ALMNAGAA | |
| SCHEMBL14034513 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL4249071 | 0.81 | GAA (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL13701756 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2KMT2ACD274HPGD | |
| SCHEMBL14007204 | 0.80 | HRH3 (0.58) | ALDH1A1SMN1; SMN2GAACD274HPGD | |
| SCHEMBL4251833 | 0.77 | BRD4 (0.42) | ALDH1A1SMN1; SMN2MAPTLMNAGAA | |
| SCHEMBL13702304 | 0.77 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2GAACD274HPGD | |
| SCHEMBL25078428 | 0.77 | BRD4 (0.45) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |
| US-9617216-B2 | Antifungal oxodihydropyridinecarbohydrazide derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
| EP-3060549-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2016-08-31 | — | — | EP | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |
| WO-2015060613-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-30 | — | — | WO | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | ELDRUP ANNE BETTINA | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | PITHD1, HPD, QDPR | ALDH1A1 773/4885SMN1; SMN2 4819/4885MAPT 3815/4885 |
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | EPHX1, EPHX2, DOHH | ALDH1A1 292/4885SMN1; SMN2 3162/4885MAPT 4662/4885 |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | ALDH1A1 376/4885SMN1; SMN2 4398/4885MAPT 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.