SCHEMBL425131

SCHEMBL425131

COc1cc(Br)ccc1CC#N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.51
CSNK2A1 P68400 2/20 0.45
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30454901 1.00 PYCR1 (0.51) PYCR1CSNK2A1KDM4ETDP1GAA
SCHEMBL4171690 0.86 KDM4E (0.50) CSNK2A1KDM4ETDP1GAAMAPT
SCHEMBL14097993 0.84 SLC6A4 (0.43) PYCR1CSNK2A1KDM4ETDP1
SCHEMBL27869012 0.83 PYCR1 (0.49) PYCR1KDM4ETDP1CASP1HSD17B10
SCHEMBL15820790 0.83 CSNK2A1 (0.43) PYCR1CSNK2A1TDP1GAAMAPT
SCHEMBL15820910 0.80 HPGD (0.46) PYCR1CSNK2A1KDM4EGAAMAPT
SCHEMBL12257908 0.80 ACHE (0.50) KDM4ETDP1GAAMAPTHTT
SCHEMBL1237860 0.80 APLNR (0.58) MAPTTSHRALDH1A1
SCHEMBL6674914 0.79 MAPT (0.65) KDM4EGAAMAPTHTTTSHR
SCHEMBL8032757 0.79 MAOB (0.50) GAAMAPTHTTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4614641-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-10 EP claimed
EP-4611154-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP claimed
EP-4611095-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP claimed
EP-4611093-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP claimed
US-20250273816-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK INNOVATION CO., LTD. (KR) 2025-08-28 US claimed
US-20250273821-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK IE TECHNOLOGY CO., LTD. (KR) 2025-08-28 US claimed
US-20250273741-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK IE TECHNOLOGY CO., LTD. (KR) 2025-08-28 US claimed
US-20250273815-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK INNOVATION CO., LTD. (KR) 2025-08-28 US claimed
US-20250023193-A1 HYBRID SEPARATOR AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME SK INNOVATION CO., LTD. (KR) 2025-01-16 US claimed
EP-4492531-A2 HYBRID SEPARATOR AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME SK Innovation Co., Ltd. (KR) 2025-01-15 EP claimed
EP-4614641-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-10 EP disclosed
EP-4611095-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP disclosed
EP-4611154-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP disclosed
EP-4611093-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK Innovation Co., Ltd. (KR) 2025-09-03 EP disclosed
US-20250273815-A1 ELECTROCHEMICAL DEVICE INCLUDING POROUS SEPARATOR SK INNOVATION CO., LTD. (KR) 2025-08-28 US disclosed
US-20070293511-A1 Crf Receptor Antagonists and Methods SB PHARMCO PUERTO RICO INC. AND NEUROCRINE BIOSCIENCES, INC., A CORPORATION 2007-12-20 US disclosed
WO-2007103432-A2 USE OF PYRAZOLO[1,5A]PYRIMIDIN-7-YL AMINE DERIVATIVES IN THE TREATMENT OF NEUROLOGICAL DISORDERS NOVARTIS AG (CH) 2007-09-13 WO disclosed
EP-1708710-A1 PYRAZOLO[1,5-A]PYRIMIDIN-7-YL-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES Novartis AG (CH) 2006-10-11 EP disclosed
US-20050222171-A1 Organic compounds NOVARTIS AG (CH) 2005-10-06 US disclosed
WO-2005070431-A1 PYRAZOLO[1,5-A]PYRIMIDIN-7-YL-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES NOVARTIS AG (CH) 2005-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293511-A1 Crf Receptor Antagonists and Methods CRHR1, CRHR2, CRH PYCR1 1525/4885CSNK2A1 1607/4885KDM4E 4388/4885
US-20050222171-A1 Organic compounds JAK1, MAP3K5, MAP3K7 PYCR1 672/4885CSNK2A1 288/4885KDM4E 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.