SCHEMBL42514

SCHEMBL42514

NC(=O)c1cc([N+](=O)[O-])[nH]n1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.52
CYP3A4 P08684 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.36
LMNA P02545 4/20 0.35
MAPT P10636 2/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
PARP1 P09874 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
KCNMA1 Q12791 2/20 0.33
DYRK1A Q13627 1/20 0.33
GAA P10253 1/20 0.33
NPC1 O15118 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
DAO P14920 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26820 0.83 HPGD (0.54) HPGDDAOHCAR2
SCHEMBL5013388 0.81 HPGD (0.52) HPGDSMN1; SMN2TSHRLMNAMAPT
Hydrochloric Acid SCHEMBL27727584 0.81 HPGD (0.52) HPGDDAOHCAR2
SCHEMBL15981916 0.81 HPGD (0.52) HPGDLMNAMAPTKMT2AALDH1A1
SCHEMBL17928435 0.78 HPGD (0.49) HPGDCYP3A4SMN1; SMN2LMNAMAPT
SCHEMBL14620257 0.77 HPGD (0.49) HPGDMAPTALDH1A1DYRK1ADAO
SCHEMBL18680106 0.77 HPGD (0.49) HPGDSMN1; SMN2LMNAMAPTKMT2A
SCHEMBL6305513 0.77 HPGD (0.49) HPGDLMNAKMT2AALDH1A1DYRK1A
SCHEMBL25449 0.77 MAPK1 (0.57) HPGDSMN1; SMN2MAPTKMT2ADYRK1A
SCHEMBL13248190 0.75 HPGD (0.56) HPGDTSHRMAPTBLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 US claimed
US-20240123045-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-04-18 US claimed
EP-4297874-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-01-03 EP claimed
WO-2022180251-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2022-09-01 WO claimed
US-11079372-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2021-08-03 US claimed
US-10775281-B2 Polymer stabilization of chromogen solutions VENTANA MEDICAL SYSTEMS, INC. (US) 2020-09-15 US claimed
EP-2686438-B1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR VENTANA MED SYST INC (US) 2018-04-18 EP claimed
EP-3201628-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME Ventana Medical Systems, Inc. (US) 2017-08-09 EP claimed
US-20170205399-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. 2017-07-20 US claimed
WO-2016050913-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-07 WO claimed
CN-103534359-A A method of analyzing chromosomal translocations and a system therefore VENTANA MED SYST INC 2014-01-22 CN claimed
EP-4707404-A2 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION Ventana Medical Systems, Inc. (US) 2026-03-11 EP disclosed
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 US disclosed
US-12553886-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-17 US disclosed
EP-3492919-B1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2026-01-21 EP disclosed
US-20040077557-A1 Macrolide antibiotics GLAXO GROUP LIMITED (GB) 2004-04-22 US disclosed
EP-1363925-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2003-11-26 EP disclosed
WO-2003057676-A1 3,4-DI-SUBSTITUTED PYRIDAZINEDIONES AS CXC CHEMOKINE RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-07-17 WO disclosed
WO-2003031440-A1 3,4-DI-SUBSTITUTED MALEIMIDE COMPOUNDS AS CXC-CHEMOKINE RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-04-17 WO disclosed
WO-2002050091-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2002-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12553886-B2 Polymers and conjugates comprising the same POLL, INCENP, POLI HPGD 1904/4885CYP3A4 2768/4885SMN1; SMN2 1052/4885
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME POLD1, POLL, INCENP HPGD 1891/4885CYP3A4 2165/4885SMN1; SMN2 1392/4885
US-20040077557-A1 Macrolide antibiotics MALT1, MRPL21, IL1R1 HPGD 2843/4885CYP3A4 500/4885SMN1; SMN2 3041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.