SCHEMBL42514

SCHEMBL42514

NC(=O)c1cc([N+](=O)[O-])[nH]n1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.52
▸ CYP3A4 P08684 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ TSHR P16473 2/20 0.36
▸ LMNA P02545 4/20 0.35
▸ MAPT P10636 2/20 0.35
▸ BLM P54132 1/20 0.35
▸ PMP22 Q01453 1/20 0.35
▸ PARP1 P09874 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ SIRT2 Q8IXJ6 1/20 0.34
▸ KCNMA1 Q12791 2/20 0.33
▸ DYRK1A Q13627 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ DAO P14920 1/20 0.32
▸ HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26820 0.83 HPGD (0.54) HPGDDAOHCAR2
SCHEMBL15981916 0.81 HPGD (0.52) HPGDLMNAMAPTKMT2AALDH1A1
Hydrochloric Acid SCHEMBL27727584 0.81 HPGD (0.52) HPGDDAOHCAR2
SCHEMBL5013388 0.81 HPGD (0.52) HPGDSMN1; SMN2TSHRLMNAMAPT
SCHEMBL17928435 0.78 HPGD (0.49) HPGDCYP3A4SMN1; SMN2LMNAMAPT
SCHEMBL25449 0.77 MAPK1 (0.57) HPGDSMN1; SMN2MAPTKMT2ADYRK1A
SCHEMBL6305513 0.77 HPGD (0.49) HPGDLMNAKMT2AALDH1A1DYRK1A
SCHEMBL14620257 0.77 HPGD (0.49) HPGDMAPTALDH1A1DYRK1ADAO
SCHEMBL18680106 0.77 HPGD (0.49) HPGDSMN1; SMN2LMNAMAPTKMT2A
SCHEMBL13248190 0.75 HPGD (0.56) HPGDTSHRMAPTBLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 — — US claimed
US-20240123045-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-04-18 — — US claimed
EP-4297874-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-01-03 — — EP claimed
WO-2022180251-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2022-09-01 — — WO claimed
US-11079372-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2021-08-03 — — US claimed
US-10775281-B2 Polymer stabilization of chromogen solutions VENTANA MEDICAL SYSTEMS, INC. (US) 2020-09-15 — — US claimed
EP-2686438-B1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR VENTANA MED SYST INC (US) 2018-04-18 — — EP claimed
EP-3201628-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME Ventana Medical Systems, Inc. (US) 2017-08-09 — — EP claimed
US-20170205399-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. 2017-07-20 — — US claimed
WO-2016050913-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-07 — — WO claimed
CN-103534359-A A method of analyzing chromosomal translocations and a system therefore VENTANA MED SYST INC 2014-01-22 — — CN claimed
EP-4707404-A2 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION Ventana Medical Systems, Inc. (US) 2026-03-11 — — EP disclosed
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 — — US disclosed
US-12553886-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-17 — — US disclosed
EP-3492919-B1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2026-01-21 — — EP disclosed
US-20040077557-A1 Macrolide antibiotics GLAXO GROUP LIMITED (GB) 2004-04-22 — — US disclosed
EP-1363925-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2003-11-26 — — EP disclosed
WO-2003057676-A1 3,4-DI-SUBSTITUTED PYRIDAZINEDIONES AS CXC CHEMOKINE RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-07-17 — — WO disclosed
WO-2003031440-A1 3,4-DI-SUBSTITUTED MALEIMIDE COMPOUNDS AS CXC-CHEMOKINE RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-04-17 — — WO disclosed
WO-2002050091-A1 MACROLIDE ANTIBIOTICS GLAXO GROUP LIMITED (GB) 2002-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12553886-B2 Polymers and conjugates comprising the same POLL, INCENP, POLI HPGD 1904/4885CYP3A4 2768/4885SMN1; SMN2 1052/4885
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME POLD1, POLL, INCENP HPGD 1891/4885CYP3A4 2165/4885SMN1; SMN2 1392/4885
US-20040077557-A1 Macrolide antibiotics MALT1, MRPL21, IL1R1 HPGD 2843/4885CYP3A4 500/4885SMN1; SMN2 3041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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