Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416802 | 0.83 | AOC3 (0.49) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL4248111 | 0.83 | AOC3 (0.45) | ALDH1A1MAPTKDM4EL3MBTL1AOC3 | |
| SCHEMBL4397006 | 0.83 | L3MBTL1 (0.42) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL4247537 | 0.82 | L3MBTL1 (0.58) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL4245848 | 0.79 | CA1 (0.51) | ALDH1A1MAPTL3MBTL1AOC3HDAC6 | |
| SCHEMBL11792163 | 0.73 | L3MBTL1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AAOC3 | |
| SCHEMBL17967143 | 0.73 | HDAC1 (0.57) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL4385002 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL2117009 | 0.72 | HDAC6 (0.77) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL4249311 | 0.70 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |