Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119371 | 0.83 | PDE4B (0.51) | L3MBTL1HTTMAPTALDH1A1NPC1 | |
| SCHEMBL4248111 | 0.82 | AOC3 (0.45) | L3MBTL1HTTMAPTALDH1A1RAB9A | |
| SCHEMBL23857357 | 0.79 | MEP1B (0.58) | CA1CA2HTTMAPTALDH1A1 | |
| SCHEMBL4251995 | 0.79 | ALDH1A1 (0.47) | L3MBTL1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4416802 | 0.79 | AOC3 (0.49) | CA1CA2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL4397006 | 0.79 | L3MBTL1 (0.42) | L3MBTL1HTTMAPTALDH1A1HDAC3 | |
| SCHEMBL4247537 | 0.78 | L3MBTL1 (0.58) | L3MBTL1HTTMAPTALDH1A1TP53 | |
| SCHEMBL19043180 | 0.76 | MAPT (0.61) | CA1CA2HTTMAPTALDH1A1 | |
| SCHEMBL13903016 | 0.76 | ALDH1A1 (0.67) | CA1CA2L3MBTL1HTTMAPT | |
| SCHEMBL10686678 | 0.75 | PPARG (0.53) | L3MBTL1HTTMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |