Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250578 | 0.85 | RAB9A (0.41) | AOC3KDM4EPOLBL3MBTL1MMP2 | |
| SCHEMBL4251995 | 0.83 | ALDH1A1 (0.47) | AOC3KDM4EPOLBL3MBTL1MAPT | |
| SCHEMBL4397006 | 0.83 | L3MBTL1 (0.42) | AOC3KDM4EL3MBTL1MAPTHTT | |
| SCHEMBL4416802 | 0.83 | AOC3 (0.49) | AOC3KDM4EPOLBL3MBTL1MAPT | |
| SCHEMBL4247537 | 0.82 | L3MBTL1 (0.58) | AOC3KDM4EL3MBTL1MAPTHTT | |
| SCHEMBL4245848 | 0.82 | CA1 (0.51) | AOC3L3MBTL1MAPTHTTRAB9A | |
| SCHEMBL2805280 | 0.82 | KMT2A (0.50) | POLBL3MBTL1MAPTHTTTSHR | |
| SCHEMBL11792163 | 0.77 | L3MBTL1 (0.51) | AOC3L3MBTL1MAPTHTTTSHR | |
| SCHEMBL14557227 | 0.76 | CNR2 (0.46) | L3MBTL1MAPTHTTTSHRMAPK1 | |
| SCHEMBL31037870 | 0.74 | MAPT (0.49) | L3MBTL1MAPTHTTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |