Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416802 | 0.83 | AOC3 (0.49) | L3MBTL1AOC3KCNH2ALDH1A1HDAC6 | |
| SCHEMBL4251995 | 0.83 | ALDH1A1 (0.47) | L3MBTL1AOC3ALDH1A1GAAHDAC6 | |
| SCHEMBL4248111 | 0.83 | AOC3 (0.45) | L3MBTL1AOC3ALDH1A1HDAC6HDAC3 | |
| SCHEMBL4247537 | 0.82 | L3MBTL1 (0.58) | L3MBTL1AOC3KCNH2ALDH1A1GAA | |
| SCHEMBL4245848 | 0.79 | CA1 (0.51) | L3MBTL1AOC3ALDH1A1HDAC6HDAC3 | |
| SCHEMBL11792163 | 0.73 | L3MBTL1 (0.51) | L3MBTL1AOC3ALDH1A1GAAMAPT | |
| SCHEMBL27606163 | 0.73 | LMNA (0.53) | AOC3ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL8216746 | 0.71 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL5504743 | 0.71 | MAPT (0.47) | L3MBTL1AOC3ALDH1A1GAAMAPT | |
| SCHEMBL19026948 | 0.71 | POLQ (0.47) | AOC3ALDH1A1GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |