SCHEMBL425219

SCHEMBL425219

C[n+]1ccn(CC(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
PLA2G1B P04054 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
LMNA P02545 1/20 0.36
PON1 P27169 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL2679835 0.86 FDPS (0.46) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL2934584 0.83 FDPS (0.40) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL13780862 0.80 FDPS (0.49) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL4279720 0.80 FDPS (0.49) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL5585615 0.75 SMN1; SMN2 (0.46) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL422818 0.75 FDPS (0.33) FDPSSMN1; SMN2MEN1HSP90AA1KMT2A
SCHEMBL15136817 0.74 SMN1; SMN2 (0.63) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL988007 0.74 SMN1; SMN2 (0.52) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL6864946 0.72 SMN1; SMN2 (0.43) FDPSSMN1; SMN2MEN1APAF1NPC1
SCHEMBL1219186 0.72 FDPS (0.33) FDPSSMN1; SMN2MEN1HSP90AA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9724804-B2 Methods of forming cutting elements by oxidizing metal in interstitial spaces in polycrystalline material BAKER HUGHES INCORPORATED (US) 2017-08-08 US claimed
US-20150114846-A1 METHODS OF FORMING CUTTING ELEMENTS BY OXIDIZING METAL IN INTERSTITIAL SPACES IN POLYCRYSTALLINE MATERIAL BAKER HUGHES HOLDINGS LLC 2015-04-30 US claimed
US-8961630-B2 Methods of forming cutting elements by removing metal from interstitial spaces in polycrystalline diamond BAKER HUGHES INCORPORATED (US) 2015-02-24 US claimed
EP-1960345-B1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, AND N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORP (US) 2014-11-19 EP claimed
US-20130291447-A1 METHODS OF FORMING CUTTING ELEMENTS BY REMOVING METAL FROM INTERSTITIAL SPACES IN POLYCRYSTALLINE DIAMOND BAKER HUGHES INCORPORATED (US) 2013-11-07 US claimed
EP-1963253-B1 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORP (US) 2011-01-05 EP claimed
EP-1960344-B1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORP (US) 2010-09-29 EP claimed
US-7563929-B2 Alkylation of N′-phenyl-N-alkylphenylenediamines in ionic liquid and N′-phenyl-N-alkyl(alkylphenylene) diamines produced thereby CHEMTURA CORPORATION (US) 2009-07-21 US claimed
US-20080234517-A1 ALKYLATION OF N'-PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID AND N'-PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORPORATION (US) 2008-09-25 US claimed
EP-1960345-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2008-08-27 EP claimed
US-7378554-B2 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORPORATION (US) 2008-05-27 US claimed
WO-2007070282-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2007-06-21 WO claimed
US-20070135656-A1 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-7145038-B1 Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORPORATION (US) 2006-12-05 US claimed
US-20240097194-A1 IONIC LIQUID, SECONDARY BATTERY, ELECTRONIC DEVICE, AND VEHICLE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-03-21 US disclosed
US-9724804-B2 Methods of forming cutting elements by oxidizing metal in interstitial spaces in polycrystalline material BAKER HUGHES INCORPORATED (US) 2017-08-08 US disclosed
US-7145038-B1 Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORPORATION (US) 2006-12-05 US disclosed
EP-0718288-B1 Liquid hydrophobic salts, their preparation and their use in electrochemistry HYDRO QUEBEC (CA) 2005-06-29 EP disclosed
EP-0718288-A1 Liquid hydrophobic salts, their preparation and their use in electrochemistry ASULAB S.A. (CH) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234517-A1 ALKYLATION OF N'-PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID AND N'-PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY PNMT, PNN, INMT FDPS 2376/4885SMN1; SMN2 1972/4885MEN1 2662/4885
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same NAPEPLD, PNN, ACR FDPS 3884/4885SMN1; SMN2 2107/4885MEN1 3476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.