Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680015 | 0.86 | OPRK1 (0.52) | ALDH1A1LMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL4283460 | 0.79 | ALDH1A1 (0.58) | ALDH1A1GAALMNAPOLBKDM4E | |
| SCHEMBL4251279 | 0.78 | ALDH1A1 (0.40) | ALDH1A1POLBKDM4EACHETHRB | |
| SCHEMBL7212540 | 0.77 | SETD7 (0.52) | ALDH1A1LMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL4128743 | 0.77 | PDE4B (0.51) | ALDH1A1LMNAPOLBPDE4D | |
| SCHEMBL4126956 | 0.76 | PDE4D (0.50) | LMNAPOLBPDE4D | |
| SCHEMBL4120097 | 0.76 | PDE4D (0.50) | ALDH1A1LMNAMEN1KMT2APDE4D | |
| SCHEMBL4255074 | 0.76 | PDE4D (0.53) | ALDH1A1LMNAMEN1KMT2APDE4D | |
| SCHEMBL10541414 | 0.75 | KMT2A (0.56) | ALDH1A1LMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL10540938 | 0.75 | KMT2A (0.50) | ALDH1A1HTR1AADRA2ACYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176802-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | PAPADOPOULOS VASSILIOS | 2009-07-09 | — | — | US | disclosed |
| US-20060247248-A1 | Sigma-1 receptor ligand with acetylcholinesterase | SAMARITAN PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247248-A1 | Sigma-1 receptor ligand with acetylcholinesterase | SIGMAR1, CHRNE, ACHE | ALDH1A1 691/4885GAA 1683/4885LMNA 2903/4885 |
| US-20090176802-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | INA, ACHE, NLN | ALDH1A1 1194/4885GAA 355/4885LMNA 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.