Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 4/20 | 0.65 |
| ▸ | MGAM | O43451 | 8/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | SI | P14410 | 8/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425552 | 0.83 | KMT2A (0.59) | F12MGAMAMY1AGAASI | |
| SCHEMBL427308 | 0.81 | KMT2A (0.70) | F12MGAMAMY1AGAASI | |
| SCHEMBL7899312 | 0.79 | KMT2A (0.59) | F12MGAMAMY1AGAASI | |
| SCHEMBL425440 | 0.78 | F12 (0.60) | F12MGAMAMY1AGAASI | |
| SCHEMBL425777 | 0.77 | KMT2A (0.56) | F12MGAMAMY1AGAASI | |
| SCHEMBL425007 | 0.76 | KMT2A (0.61) | F12MGAMAMY1AGAASI | |
| SCHEMBL426868 | 0.75 | F12 (0.53) | F12MGAMAMY1AGAASI | |
| SCHEMBL424474 | 0.74 | MGAM (0.58) | F12MGAMAMY1AGAASI | |
| SCHEMBL424354 | 0.73 | KMT2A (0.51) | F12MGAMAMY1AGAASI | |
| SCHEMBL2494948 | 0.72 | MGAM (1.00) | F12MGAMAMY1AGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | F12 785/4885MGAM 1034/4885AMY1A 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.