Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 10/20 | 0.55 |
| ▸ | MGAM | O43451 | 9/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.55 |
| ▸ | SI | P14410 | 9/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.55 |
| ▸ | F12 | P00748 | 6/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425007 | 0.84 | KMT2A (0.61) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL425552 | 0.79 | KMT2A (0.59) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL427308 | 0.78 | KMT2A (0.70) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL459733 | 0.78 | GAA (0.60) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL425444 | 0.77 | F12 (0.65) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL445704 | 0.75 | GAA (0.52) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL7899312 | 0.75 | KMT2A (0.59) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL425437 | 0.75 | GAA (0.52) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL427748 | 0.75 | GAA (0.52) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL3371897 | 0.75 | GAA (0.57) | HTTGAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | KMT2A 2067/4885MAPT 1705/4885NPSR1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.