Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260752 | 0.87 | ESR1 (0.52) | MEN1KMT2AALDH1A1ESR1MCHR1 | |
| SCHEMBL4253697 | 0.87 | ALDH1A1 (0.50) | MEN1KMT2ARAB9AALDH1A1HSD17B10 | |
| SCHEMBL4256269 | 0.86 | NR1H3 (0.52) | MEN1KMT2AMCHR1HTT | |
| SCHEMBL4259106 | 0.86 | CYP3A4 (0.43) | MEN1KMT2ARAB9AALDH1A1ESR1 | |
| SCHEMBL4250037 | 0.86 | CYP3A4 (0.50) | MEN1KMT2ARAB9AALDH1A1ESR1 | |
| SCHEMBL4253067 | 0.86 | ESR1 (0.52) | MEN1KMT2ARAB9AALDH1A1ESR1 | |
| SCHEMBL4251879 | 0.78 | NPC1 (0.45) | RAB9AALDH1A1NPC1TSHRMCHR1 | |
| SCHEMBL4253075 | 0.78 | NPC1 (0.47) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL16602061 | 0.76 | CA9 (0.75) | MEN1KMT2ARAB9ACA9CA12 | |
| SCHEMBL4256256 | 0.76 | CA9 (0.61) | MEN1KMT2ARAB9ACA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054653-A2 | ISOINDOLONES WITH HIGH BINDING AFFINITY TO BETA-AMYLOID AGGREGATES AND FIBRILS, AND ITS USE AND PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-04-30 | — | — | WO | claimed |
| WO-2009054653-A2 | ISOINDOLONES WITH HIGH BINDING AFFINITY TO BETA-AMYLOID AGGREGATES AND FIBRILS, AND ITS USE AND PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-04-30 | — | — | WO | disclosed |