Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629704 | 0.86 | TSHR (0.41) | TSHRIDO1AGXTLMNAMAOB | |
| SCHEMBL8701365 | 0.86 | IDO1 (0.45) | IDO1AGXTLMNAMAOBMAOA | |
| SCHEMBL6672654 | 0.85 | TSHR (0.56) | TSHRIDO1AGXTLMNAMAOB | |
| SCHEMBL9550750 | 0.84 | MAOB (0.51) | LMNAMAOBMAOALCKSMN1; SMN2 | |
| SCHEMBL18797756 | 0.82 | LMNA (0.41) | TSHRIDO1LMNAMAOBLCK | |
| SCHEMBL7565432 | 0.82 | LTA4H (0.53) | TSHRIDO1AGXTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9798232 | 0.82 | ALDH1A1 (0.39) | TSHRIDO1LMNAMAOBMAOA | |
| SCHEMBL8333879 | 0.81 | TSHR (0.52) | TSHRIDO1AGXTLMNAMAOB | |
| SCHEMBL5244736 | 0.81 | NFE2L2 (0.52) | IDO1AGXTMAOBMAOALCK | |
| SCHEMBL2068701 | 0.78 | TSHR (0.52) | TSHRIDO1AGXTLMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177249-A1 | NOVEL BINARY HISTONE DEACETYLASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 숙명여자대학교산학협력단 | 2023-09-21 | — | — | WO | claimed |
| WO-2023177250-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 숙명여자대학교산학협력단 | 2023-09-21 | — | — | WO | claimed |
| CN-113874375-A | Cyclic amide compounds and methods thereof for the treatment of rabies | 株式会社大分大学先端医学研究所 | 2021-12-31 | — | — | CN | claimed |
| WO-2020246503-A1 | CYCLIC AMIDE COMPOUNDS FOR RABIES TREATMENT AND METHOD THEREOF | 株式会社大分大学先端医学研究所 | 2020-12-10 | — | — | WO | claimed |
| CN-111448280-A | Photosensitizer and active energy ray-curable composition | 积水化学工业株式会社 | 2020-07-24 | — | — | CN | claimed |
| EP-2951179-B1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | MERCK PATENT GMBH (DE) | 2020-03-11 | — | — | EP | claimed |
| WO-2019155989-A1 | PHOTOSENSITIZER AND ACTIVE ENERGY RAY-CURABLE COMPOSITION | 積水化学工業株式会社 | 2019-08-15 | — | — | WO | claimed |
| CN-107924124-A | Negative photoresist composition for I-line with excellent etching resistance | 荣昌化学制品株式会社 | 2018-04-17 | — | — | CN | claimed |
| US-9708321-B2 | Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2017-07-18 | — | — | US | claimed |
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2015-12-17 | — | — | US | claimed |
| US-4599361-A | ANTIARTHRITIC | G. D. SEARLE & CO. (US) | 1986-07-08 | — | — | US | claimed |
| EP-0185380-A2 | Thiol based collagenase inhibitors | G.D. Searle & Co. (US) | 1986-06-25 | — | — | EP | claimed |
| US-4595700-A | Thiol based collagenase inhibitors | G. D. SEARLE & CO. (US) | 1986-06-17 | — | — | US | claimed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | claimed |
| US-4436726-A | TREATMENT OF IMMUNE DEFICIENCY DISEASES AND THROMBOSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | claimed |
| EP-0054435-B1 | N-ACYL PEPTIDE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-25 | — | — | EP | claimed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | claimed |
| EP-0054435-A1 | N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-23 | — | — | EP | claimed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | GRM4, GRIA4, GRIK4 | TSHR 839/4885IDO1 4185/4885AGXT 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.