Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410674 | 0.85 | TRPA1 (0.39) | ALDH1A1MAOBTSHRIDO1RELA | |
| SCHEMBL425560 | 0.82 | TSHR (0.50) | ALDH1A1MAOBTSHRIDO1LMNA | |
| SCHEMBL789470 | 0.82 | RELA (0.41) | ALDH1A1MAOBTSHRLMNARELA | |
| SCHEMBL6672654 | 0.82 | TSHR (0.56) | MAOBTSHRIDO1LMNASMN1; SMN2 | |
| SCHEMBL2769032 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAOBTSHRCYP2A6IDO1 | |
| SCHEMBL93706 | 0.79 | RELA (0.47) | ALDH1A1MAOBTSHRCYP2A6IDO1 | |
| SCHEMBL7054866 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAOBTSHRCYP2A6IDO1 | |
| SCHEMBL790911 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAOBTSHRCYP2A6IDO1 | |
| SCHEMBL29135403 | 0.79 | IDO1 (0.36) | ALDH1A1MAOBTSHRCYP2A6IDO1 | |
| SCHEMBL9217606 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAOBTSHRCYP2A6IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410380-A2 | Novel process for the synthesis of 2-fluoro-1-olefins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-30 | — | — | EP | disclosed |