Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | NPY4R | P50391 | 7/20 | 0.38 |
| ▸ | NPY1R | P25929 | 5/20 | 0.38 |
| ▸ | NPY2R | P49146 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | OTC | P00480 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14771593 | 0.87 | DPP7 (0.39) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL15820093 | 0.86 | DPP7 (0.40) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8745865 | 0.86 | DPP7 (0.43) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10292018 | 0.86 | DPP7 (0.43) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL4810722 | 0.86 | DPP7 (0.40) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8214683 | 0.86 | DPP7 (0.43) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL4810699 | 0.86 | DPP7 (0.40) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| Arginine SCHEMBL1527718 | 0.85 | OTC (0.50) | OTCMEN1KMT2ACYP1A2NOS3 | |
| SCHEMBL11814623 | 0.84 | OTC (0.41) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8213398 | 0.84 | OTC (0.41) | DPP7NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011991-A1 | Novel Curcuminoid-Factor VIIA Constructs as Suppressors of Tumor Growth and Angiogenesis | EMORY UNIVERSITY | 2009-01-08 | — | — | US | claimed |
| US-20060229239-A9 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | SHOJI MAMORU | 2006-10-12 | — | — | US | claimed |
| EP-1572078-A4 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | UNIV EMORY (US) | 2006-08-09 | — | — | EP | claimed |
| EP-1572078-A2 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | Emory University (US) | 2005-09-14 | — | — | EP | claimed |
| US-20050069551-A1 | Cytotoxic compound-protein conjugates as suppressors of tumor growth and angiogenesis | EMORY UNIVERSITY | 2005-03-31 | — | — | US | claimed |
| WO-2005025623-A2 | EF-24-FACTOR VII CONJUGATES | EMORY UNIVERSITY (US) | 2005-03-24 | — | — | WO | claimed |
| US-20040009914-A1 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | US GOVERNMENT - SECRETARY OF THE ARMY | 2004-01-15 | — | — | US | claimed |
| WO-2003075847-A2 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | EMORY UNIVERSITY (US) | 2003-09-18 | — | — | WO | claimed |
| US-20080206227-A1 | FACTOR VII CONJUGATES FOR SELECTIVELY TREATING NEOVASCULARIZATION DISORDERS | YALE UNIVERSITY | 2008-08-28 | — | — | US | disclosed |
| US-20060229239-A9 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | SHOJI MAMORU | 2006-10-12 | — | — | US | disclosed |
| EP-1572078-A4 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | UNIV EMORY (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20060052286-A1 | Tissue factor targeted, photosensitized blood coagulation factor for treatment of vision and cell proliferative disorders | YALE UNIVERSITY | 2006-03-09 | — | — | US | disclosed |
| WO-2006020979-A2 | FACTOR VII CONJUGATES FOR SELECTIVELY TREATING NEOVASCULARIZATION DISORDERS | YALE UNIVERSITY (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-1572078-A2 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | Emory University (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050069551-A1 | Cytotoxic compound-protein conjugates as suppressors of tumor growth and angiogenesis | EMORY UNIVERSITY | 2005-03-31 | — | — | US | disclosed |
| WO-2005025623-A2 | EF-24-FACTOR VII CONJUGATES | EMORY UNIVERSITY (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20040009914-A1 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | US GOVERNMENT - SECRETARY OF THE ARMY | 2004-01-15 | — | — | US | disclosed |
| WO-2003075847-A2 | NOVEL CURCUMINOID-FACTOR VIIa CONSTRUCTS AS SUPPRESSORS OF TUMOR GROWTH AND ANGIOGENESIS | EMORY UNIVERSITY (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206227-A1 | FACTOR VII CONJUGATES FOR SELECTIVELY TREATING NEOVASCULARIZATION DISORDERS | F13B, F7, F5 | DPP7 319/4885NPY4R 899/4885NPY1R 1202/4885 |
| US-20060229239-A9 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | F13B, F13A1, HABP2 | DPP7 1481/4885NPY4R 2449/4885NPY1R 3669/4885 |
| US-20040009914-A1 | Novel curcuminoid-factor VIIa constructs as suppressors of tumor growth and angiogenesis | F13B, F13A1, HABP2 | DPP7 1481/4885NPY4R 2449/4885NPY1R 3669/4885 |
| US-20090011991-A1 | Novel Curcuminoid-Factor VIIA Constructs as Suppressors of Tumor Growth and Angiogenesis | F13B, F13A1, HABP2 | DPP7 1229/4885NPY4R 3409/4885NPY1R 4268/4885 |
| US-20050069551-A1 | Cytotoxic compound-protein conjugates as suppressors of tumor growth and angiogenesis | VEGFA, AGER, HDGF | DPP7 2708/4885NPY4R 1889/4885NPY1R 2288/4885 |
| US-20060052286-A1 | Tissue factor targeted, photosensitized blood coagulation factor for treatment of vision and cell proliferative disorders | F13B, TFPI, F5 | DPP7 571/4885NPY4R 1326/4885NPY1R 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.