Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256764 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL25818400 | 0.75 | THRB (0.43) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL29919652 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL28437143 | 0.72 | PDK2 (0.42) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL30741411 | 0.72 | THRB (0.50) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL30084636 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL3401845 | 0.72 | THRB (0.50) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL706442 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6THRBTDP1 | |
| SCHEMBL8984573 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HSD17B10THRBTDP1DPP4 | |
| SCHEMBL697580 | 0.71 | MEN1 (0.47) | ALDH1A1HSD17B10CYP2A6THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009074-A3 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | DOW CHEMICAL CO (US) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |