Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388324 | 0.72 | HPGD (0.80) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL3822985 | 0.72 | HPGD (0.80) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL19277755 | 0.70 | KMT2A (0.75) | GAAALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27920292 | 0.70 | HPGD (0.62) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL28638734 | 0.69 | GAA (0.67) | GAAALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11693290 | 0.68 | NPC1 (0.71) | GAAALDH1A1TDP1LMNATASP1 | |
| SCHEMBL13299603 | 0.68 | HPGD (0.68) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL4299552 | 0.67 | LMNA (0.65) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL4299548 | 0.67 | LMNA (0.65) | GAAALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL10069054 | 0.67 | TASP1 (1.00) | GAAALDH1A1TDP1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |