Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266010 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL4989028 | 0.79 | MMP12 (0.48) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL4258875 | 0.75 | FFAR1 (0.42) | NPC1RAB9ACYP1A2SMN1; SMN2L3MBTL1 | |
| SCHEMBL17193393 | 0.75 | HPGD (0.48) | HPGDALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL20553323 | 0.74 | HPGD (0.50) | HPGDALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL4261689 | 0.73 | MEN1 (0.49) | HPGDALDH1A1NPC1MAPK1USP2 | |
| SCHEMBL21713291 | 0.72 | MAOA (0.53) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5168911 | 0.71 | NPC1 (0.65) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5805293 | 0.70 | ALDH1A1 (0.43) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6509017 | 0.69 | HPGD (0.49) | HPGDALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029423-A1 | METHOD FOR SEPARATING TARGET COMPONENT | CANON KABUSHIKI KAISHA (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20070003975-A1 | Structured construct and producing method therefor | CANON KABUSHIKI KAISHA (JP) | 2007-01-04 | — | — | US | disclosed |
| WO-2004097417-A1 | STRUCTURED CONSTRUCT AND PRODUCING METHOD THEREFOR | CANON KABUSHIKI KAISHA (JP) | 2004-11-11 | — | — | WO | disclosed |