Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742539 | 0.85 | PTPN1 (0.41) | CTRB1FASNCES2CES1AKR1B1 | |
| SCHEMBL230546 | 0.84 | CTRB1 (0.36) | CTRB1FASNCES2CES1AKR1B1 | |
| SCHEMBL5004808 | 0.81 | PLA2G10 (0.39) | CTRB1FASNCES2CES1AKR1B1 | |
| SCHEMBL388934 | 0.81 | ALDH1A1 (0.36) | CTRB1FASNCES2CES1AKR1B1 | |
| SCHEMBL133894 | 0.79 | MEN1 (0.36) | CTRB1 | |
| SCHEMBL3712470 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL3369296 | 0.75 | IDO1 (0.37) | IDO1 | |
| SCHEMBL5911326 | 0.74 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL5175535 | 0.73 | L3MBTL1 (0.44) | — | |
| SCHEMBL4865516 | 0.72 | P2RX7 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846430-B1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-04-01 | — | — | EP | disclosed |