SCHEMBL4259920

SCHEMBL4259920

COC(Cc1ccc(B(O)O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.52
PPARG P37231 10/20 0.52
PPARD Q03181 5/20 0.52
SRR Q9GZT4 4/20 0.47
PSAT1 Q9Y617 2/20 0.46
CSK P41240 1/20 0.46
LDHA P00338 1/20 0.45
LPL P06858 1/20 0.44
LIPG Q9Y5X9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4263574 0.81 PPARG (0.48) PPARAPPARGPPARDSRRLPL
SCHEMBL4451311 0.81 PPARA (0.56) PPARAPPARGPPARDSRRPSAT1
SCHEMBL4941128 0.81 PPARA (0.56) PPARAPPARGPPARDSRRPSAT1
SCHEMBL3466702 0.81 PPARA (0.56) PPARAPPARGPPARDSRRPSAT1
SCHEMBL16877217 0.80 SRR (0.70) PPARAPPARGPPARDSRRPSAT1
SCHEMBL2517934 0.80 SRR (0.70) PPARAPPARGPPARDSRRPSAT1
SCHEMBL9628212 0.80 SRR (0.70) PPARAPPARGPPARDSRRPSAT1
SCHEMBL24328239 0.79 PPARG (0.59) PPARAPPARGPPARDSRRPSAT1
SCHEMBL5606722 0.79 PPARA (0.55) PPARAPPARGPPARDSRRPSAT1
SCHEMBL4811729 0.79 PPARA (0.55) PPARAPPARGPPARDSRRPSAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090048258-A1 Amide Compound TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-19 US disclosed
EP-1845081-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2007-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048258-A1 Amide Compound DLAT, DGAT1, DGAT2 PPARA 323/4885PPARG 80/4885PPARD 924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.