Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855918 | 0.83 | CA1 (0.48) | CA1CA2NAPRTALDH1A1CA12 | |
| SCHEMBL29773884 | 0.83 | NAPRT (0.47) | CA1CA2NAPRTALDH1A1TSHR | |
| SCHEMBL979398 | 0.83 | NAPRT (0.47) | CA1CA2NAPRTALDH1A1TSHR | |
| SCHEMBL29881883 | 0.82 | HTT (0.41) | NAPRTALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL18864821 | 0.82 | HTT (0.41) | NAPRTALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL29186263 | 0.81 | NAPRT (0.45) | CA1CA2NAPRTALDH1A1TSHR | |
| SCHEMBL625580 | 0.81 | SMN1; SMN2 (0.47) | CA1CA2NAPRTALDH1A1CA12 | |
| SCHEMBL29446081 | 0.81 | SMN1; SMN2 (0.47) | CA1CA2NAPRTALDH1A1CA12 | |
| SCHEMBL915144 | 0.78 | ALDH1A1 (0.45) | CA1CA2NAPRTALDH1A1CA12 | |
| SCHEMBL13360245 | 0.78 | LDHA (0.46) | CA1CA2NAPRTALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161297-A | Preparation method of 4-bromo-6-chloronicotinic acid methyl ester | 浙江工业大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-116782996-A | Tautomeric ligands enable biomimetic C-H hydroxylation under molecular oxygen | 斯克里普斯研究学院 | 2023-09-19 | — | — | CN | disclosed |
| EP-2417121-A1 | 4, 5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | Pfizer Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120022058-A1 | 4,5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | PFIZER INC. | 2012-01-26 | — | — | US | disclosed |
| WO-2010116282-A1 | 4, 5-DIHYDRO-LH-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-0700399-B1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | LEPETIT SPA (IT) | 2001-10-04 | — | — | EP | disclosed |
| US-5786350-A | CONDENSATION; HYDROLYSIS; DEPROTECTING | GRUPPO LEPETIT S.P.A. (IT) | 1998-07-28 | — | — | US | disclosed |
| EP-0700399-A1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994028002-A1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022058-A1 | 4,5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | NR3C2, REN, AGTR1 | CA1 4577/4885CA2 2643/4885NAPRT 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.