SCHEMBL915144

SCHEMBL915144

O=C(O)c1cnc(O)cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA12 O43570 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA14 Q9ULX7 3/20 0.45
TSHR P16473 1/20 0.45
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA2 P47869 2/20 0.42
GABRB2 P47870 2/20 0.42
GABRA4 P48169 2/20 0.42
GABRE P78334 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11810502 0.89 ALDH1A1 (0.37) ALDH1A1CA1CA2CA12CA7
SCHEMBL23854026 0.82 CA1 (0.45) ALDH1A1CA1CA2CA12CA7
SCHEMBL13360245 0.82 LDHA (0.46) ALDH1A1CA1CA2CA12CA7
SCHEMBL15793363 0.80 KDM4E (0.57) ALDH1A1CA1CA2CA12CA7
SCHEMBL9505997 0.80 NNMT (0.42) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL17971177 0.80 CES2 (0.31) ALDH1A1CA1CA2CA12CA7
SCHEMBL4842186 0.78 CA1 (0.42) ALDH1A1CA1CA2CA12CA7
SCHEMBL5336718 0.78 GABRP (0.63) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL426192 0.78 CA1 (0.44) ALDH1A1CA1CA2CA12CA7
SCHEMBL5356192 0.78 GABRP (0.63) ALDH1A1CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349873-B High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2023-03-17 CN claimed
CN-114349873-A High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2022-04-15 CN claimed
WO-2024127363-A1 TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF ALEMBIC PHARMACEUTICALS LIMITED (IN) 2024-06-20 WO disclosed
CN-114349873-B High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2023-03-17 CN disclosed
CN-114349873-B High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2023-03-17 CN disclosed
WO-2022268119-A1 SULFOXIMINE COMPOUND AND USE THEREOF 南京明德新药研发有限公司 2022-12-29 WO disclosed
CN-114349873-A High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2022-04-15 CN disclosed
CN-114349873-A High-strength fan bracket for porous module auxiliary control device 杭州安誉科技有限公司 2022-04-15 CN disclosed
CN-106854177-B A kind of preparation method of 6- chloro-4-hydroxyl pyridine -3- formaldehyde 苏州健雄职业技术学院 2019-10-11 CN disclosed
US-20160222014-A1 COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS ASANA BIOSCIENCES, LLC (US) 2016-08-04 US disclosed
EP-2975027-A1 NICOTINAMIDES AS JAK KINASE MODULATORS Portola Pharmaceuticals, Inc. (US) 2016-01-20 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0909270-A4 1999-04-21 EP disclosed
EP-0909270-A1 PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-04-21 EP disclosed
WO-1997024327-A1 PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-10 WO disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-3953428-A ANTIBACTERIAL YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160222014-A1 COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS SRC, PTK2, FYN ALDH1A1 3377/4885CA1 4192/4885CA2 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.