Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050760 | 0.76 | CYP4F2 (0.50) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL4265764 | 0.76 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTHPGDHSD17B10 | |
| SCHEMBL4266618 | 0.75 | CYP4F2 (0.56) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27782843 | 0.74 | CYP4F2 (0.54) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL28581664 | 0.74 | CYP4F2 (0.61) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL6282888 | 0.74 | CYP4F2 (0.69) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| Succinic Acid Diethyl Ester SCHEMBL27940678 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL3496255 | 0.72 | ALDH1A1 (0.54) | ALDH1A1PTPN1SMN1; SMN2MAPTHPGD | |
| SCHEMBL2428470 | 0.71 | CYP4F2 (0.57) | ALDH1A1PTPN1CYP4F2CYP4A11MAPT | |
| SCHEMBL15822278 | 0.71 | ALOX5 (0.51) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | ALDH1A1 435/4885PTPN1 3426/4885CYP4F2 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.