Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | CDC42 | P60953 | 1/20 | 0.43 |
| ▸ | RAC1 | P63000 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133236 | 0.81 | AKR1C3 (0.37) | AKR1C3P2RX3 | |
| SCHEMBL15998600 | 0.79 | CNR2 (0.37) | CYP1A2P2RX3MEN1KMT2A | |
| SCHEMBL31372250 | 0.79 | KMT2A (0.49) | TSHRMEN1KMT2A | |
| SCHEMBL18360184 | 0.79 | KMT2A (0.49) | TSHRMEN1KMT2A | |
| SCHEMBL340676 | 0.77 | TSHR (0.43) | PTGS2PTGS1TSHRSLC22A6CYP1A2 | |
| SCHEMBL6935704 | 0.76 | ALDH1A1 (0.41) | P2RX3KMT2A | |
| SCHEMBL339283 | 0.76 | ALDH1A1 (0.49) | TSHRMEN1KMT2A | |
| SCHEMBL339506 | 0.75 | PARP10 (0.50) | TSHRKMT2A | |
| SCHEMBL31312752 | 0.74 | BACE1 (0.37) | P2RX3 | |
| SCHEMBL258951 | 0.74 | BACE1 (0.37) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009597-A1 | WATER SOLUBLE OLEFIN METATHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-01-15 | — | — | WO | disclosed |