SCHEMBL426367

SCHEMBL426367

CCc1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.59
KDM1A O60341 1/20 0.49
ALDH1A1 P00352 2/20 0.41
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 1/20 0.41
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
KIF11 P52732 2/20 0.39
PLAU P00749 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
LPL P06858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540403 0.92 TP53 (0.50) TP53KDM1AALDH1A1CYP2A6CYP1A2
SCHEMBL241973 0.90 TP53 (0.48) TP53KDM1AALDH1A1CYP2A6CYP1A2
SCHEMBL9608258 0.80 ACHE (0.39) TP53KDM1AALDH1A1CYP2A6CYP1A2
Ethylbenzene SCHEMBL27405402 0.79 TP53 (0.93) TP53ALDH1A1CYP2A6CYP1A2RAB9A
Benzene SCHEMBL27406821 0.79 TP53 (0.80) TP53ALDH1A1CYP2A6CYP1A2RAB9A
SCHEMBL12762155 0.79 ALDH1A1 (0.38) KDM1AALDH1A1CYP2A6CYP1A2TAAR1
SCHEMBL12748732 0.78 CALM1 (0.60) KDM4ELMNAMAPT
SCHEMBL13131224 0.77 TP53 (0.33) TP53KDM1A
Ethylbenzene SCHEMBL1332452 0.76
Ethylbenzene SCHEMBL11223212 0.76 TP53 (1.00) TP53ALDH1A1CYP2A6CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10824073-B2 Radiation-sensitive resin composition and resist pattern-forming method JSR CORPORATION (JP) 2020-11-03 US disclosed
US-9760004-B2 Radiation-sensitive resin composition and resist pattern-forming method JSR CORPORATION (JP) 2017-09-12 US disclosed
US-9760004-B2 Radiation-sensitive resin composition and resist pattern-forming method JSR CORPORATION (JP) 2017-09-12 US disclosed
WO-2017089492-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARENES USING DIARYLIODONIUM SALTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2017-06-01 WO disclosed
US-20170038679-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIST PATTERN-FORMING METHOD, ACID GENERATOR AND COMPOUND JSR CORPORATION (JP) 2017-02-09 US disclosed
US-9523911-B2 Radiation-sensitive resin composition, resist pattern-forming method, acid generator and compound JSR CORPORATION (JP) 2016-12-20 US disclosed
US-9188858-B2 Radiation-sensitive resin composition, method for forming resist pattern, acid generating agent and compound JSR CORPORATION (JP) 2015-11-17 US disclosed
US-9152044-B2 2015-10-06 US disclosed
US-9122154-B2 Radiation-sensitive resin composition, and radiation-sensitive acid generating agent JSR CORPORATION (JP) 2015-09-01 US disclosed
US-9104102-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2015-08-11 US disclosed
US-5153104-A Negative-acting photothermographic imaging systems comprising also a nitrate, an initiator, a leuco dye and a binder; colorfastness; clean background MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
EP-0500321-A1 High speed aqueous solvent developable photopolymer compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-26 EP disclosed
WO-1992009934-A1 PHOTOSENSITIVE MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-11 WO disclosed
US-5102771-A Containing photoinitiator and polymer containing alkoxyalkyl ester groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-07 US disclosed
EP-0462763-A1 Thermally developable light-sensitive layers containing photobleachable sensitizers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-27 EP disclosed
EP-0302610-A2 Light sensitive element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-02-08 EP disclosed
EP-0061898-B1 VISIBLE LIGHT SENSITIVE, THERMALLY DEVELOPABLE IMAGING SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-19 EP disclosed
US-4460677-A Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
US-4386154-A ACYLATED LEUCO DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-31 US disclosed
EP-0061898-A1 Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170038679-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIST PATTERN-FORMING METHOD, ACID GENERATOR AND COMPOUND RER1, ASIC1, GAR1 TP53 4441/4885KDM1A 1032/4885ALDH1A1 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.