SCHEMBL426370

SCHEMBL426370

O=[N+]([O-])c1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
LMNA P02545 1/20 0.62
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CRHBP P24387 2/20 0.53
CRHR2 Q13324 2/20 0.53
ATM Q13315 1/20 0.53
TLR9 Q9NR96 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
PTPRF P10586 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN1 P18031 1/20 0.50
PTPN11 Q06124 1/20 0.50
POLB P06746 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31093480 0.98 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL31145688 0.98 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL424558 0.91 ALDH1A1 (0.54) ALDH1A1LMNACES1TDP1ACHE
Hydrochloric Acid SCHEMBL11060473 0.89 ALDH1A1 (0.52) ALDH1A1LMNACES1POLBTDP1
SCHEMBL2904040 0.86 MMP2 (0.48) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL5400366 0.85 CA2 (0.50) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL2903525 0.85 ALDH1A1 (0.46) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL31058260 0.84 TSHR (0.57) ALDH1A1LMNAKMT2ACES1CES2
SCHEMBL52022 0.84 ALDH1A1 (0.48) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL31058175 0.83 ALDH1A1 (0.46) ALDH1A1LMNACES1TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565378-B1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-05-06 EP claimed
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-01-15 US claimed
EP-4565378-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA Sicpa Holding SA (CH) 2025-06-11 EP claimed
US-12311406-B2 Methods for producing optical effect layers comprising magnetic or magnetizable pigment particles and exhibiting one or more indicia SICPA HOLDING SA (CH) 2025-05-27 US claimed
US-20240238839-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2024-07-18 US claimed
WO-2024028408-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2024-02-08 WO claimed
EP-4313430-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA Sicpa Holding SA (CH) 2024-02-07 EP claimed
WO-2022207692-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2022-10-06 WO claimed
EP-4565378-B1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-05-06 EP disclosed
EP-4352175-B1 HYBRID UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2026-02-25 EP disclosed
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-01-15 US disclosed
US-12391841-B2 Hybrid UV-LED radiation curable protective varnishes for security documents SICPA HOLDING SA (CH) 2025-08-19 US disclosed
US-12311406-B2 Methods for producing optical effect layers comprising magnetic or magnetizable pigment particles and exhibiting one or more indicia SICPA HOLDING SA (CH) 2025-05-27 US disclosed
WO-2025051659-A1 UV-VIS CURABLE SECURITY INKS COMPRISING TAGS AND SECURITY FEATURES OBTAINED THEREOF SICPA HOLDING SA (CH) 2025-03-13 WO disclosed
US-6821705-B2 USED AS CHEMICALLY AMPLIFIED RESIST, EXHIBITS HIGH SENSITIVITY, RESOLUTION, RADIATION TRANSMITTANCE, AND SURFACE SMOOTHNESS, AND IS FREE FROM THE PROBLEM OF PARTIAL INSOLUBLIZATION DURING OVEREXPOSURE JSR CORPORATION (JP) 2004-11-23 US disclosed
US-20030219680-A1 Photoresists useful for microfabrication utilizing deep ultraviolet rays such as an excimer laser, x-rays such as synchrotron radiation, and electron beams JSR CORPORATION (JP) 2003-11-27 US disclosed
US-20020192593-A1 Used as chemically amplified resist, exhibits high sensitivity, resolution, radiation transmittance, and surface smoothness, and is free from the problem of partial insolublization during overexposure JSR CORPORATION (JP) 2002-12-19 US disclosed
US-20020172885-A1 Novel carbazole derivative and chemically amplified radiation-sensitive resin composition JSR CORPORATION (JP) 2002-11-21 US disclosed
EP-1238972-A1 Novel carbazole derivative and chemically amplified radiation-sensitive resin composition JSR Corporation (JP) 2002-09-11 EP disclosed
US-3952028-A ANTIMICROBIAL IODONIUM SALT INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020172885-A1 Novel carbazole derivative and chemically amplified radiation-sensitive resin composition ARID2, RAD1, RAD51 ALDH1A1 1654/4885LMNA 3785/4885MEN1 2881/4885
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA IK, TEX10, INCENP ALDH1A1 1748/4885LMNA 77/4885MEN1 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.