Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268501 | 0.94 | GPR183 (0.49) | MEN1KMT2AGPR183ALDH1A1SMN1; SMN2 | |
| SCHEMBL4270776 | 0.85 | HCAR2 (0.44) | GPR183ALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL4264349 | 0.85 | HCAR2 (0.44) | GPR183ALDH1A1MAPTRAB9AHPGD | |
| Pyrrole SCHEMBL4268503 | 0.78 | HDAC3 (0.38) | MEN1KMT2AGPR183ALDH1A1RAB9A | |
| SCHEMBL4277728 | 0.74 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL692605 | 0.71 | MEN1 (0.87) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28112899 | 0.71 | MEN1 (0.87) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL692500 | 0.71 | MEN1 (0.87) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL692499 | 0.71 | MEN1 (0.87) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4270404 | 0.71 | KMT2A (0.55) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |