Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805061 | 1.00 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL30821765 | 1.00 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| Phosphonic Acid SCHEMBL31552898 | 0.89 | MGAM (0.50) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL3868339 | 0.79 | BACE1 (0.47) | CYP1A2PDGFRBPDGFRAMAPTCYP2A6 | |
| SCHEMBL30824470 | 0.78 | ALDH1A1 (0.44) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL29378174 | 0.78 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRAMAPTCYP2A6 | |
| SCHEMBL2347880 | 0.78 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRAMAPTCYP2A6 | |
| SCHEMBL21508015 | 0.77 | CLK2 (0.46) | PDGFRBPDGFRACYP2A6BIRC5RAB9A | |
| SCHEMBL32667946 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL2772360 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3644992-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2023-03-29 | — | — | EP | claimed |
| CN-108107142-B | Analysis method of surfactant in wax removal water | 上海微谱化工技术服务有限公司 | 2020-05-22 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| EP-1687276-B1 | NOVEL METHOD OF PREPARING 3-FLUORINATED QUINOLINES | NOVEXEL (FR) | 2009-10-14 | — | — | EP | claimed |
| US-7396934-B2 | Process for preparing 3-fluoroquinolines | NOVEXEL (FR) | 2008-07-08 | — | — | US | claimed |
| US-20050182259-A1 | Subjecting a substituted quinoline-3-carboxamide compound to Hofmann degradation to obtain amine derivative, forming diazonium salt by reacting amine derivative with borontrifluoride-ethyl ether complex, heating to form 3-fluoroquinolines; intermediate for forming antibacterial compound | AVENTIS PHARMA S.A. (US) | 2005-08-18 | — | — | US | claimed |
| US-6903217-B2 | Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. (FR) | 2005-06-07 | — | — | US | claimed |
| US-20260048151-A1 | HEMICYANINE PUSH-PULL DYES BASED ON CHROMENE ELECTRON DONORS | UNIV CONNECTICUT (US) | 2026-02-19 | — | — | US | disclosed |
| CN-119775316-A | Quinoline phosphonate derivative and synthetic method and application thereof | 中苏圆科技集团有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119144124-A | Composite material and preparation method thereof, film, photoelectric device and preparation method thereof, and display device | TCL科技集团股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2024044214-A1 | HEMICYANINE PUSH-PULL DYES BASED ON CHROMENE ELECTRON DONORS | UNIVERSITY OF CONNECTICUT (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044214-A1 | HEMICYANINE PUSH-PULL DYES BASED ON CHROMENE ELECTRON DONORS | UNIVERSITY OF CONNECTICUT (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-3183250-B1 | PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL | CLAP CO LTD (KR) | 2023-10-04 | — | — | EP | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0259687-A2 | Method for the preparation of pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0257518-A1 | Quinoline-8-carboxylic acid derivatives | BASF Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4135045-A | PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4048415-A | TITANIUM-ALUMINUM COORDINATION CATALYSTS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260048151-A1 | HEMICYANINE PUSH-PULL DYES BASED ON CHROMENE ELECTRON DONORS | MB, CRY2, S100A10 | CYP1A2 1391/4885PDGFRB 1067/4885PDGFRA 795/4885 |
| US-20050182259-A1 | Subjecting a substituted quinoline-3-carboxamide compound to Hofmann degradation to obtain amine derivative, forming diazonium salt by reacting amine derivative with borontrifluoride-ethyl ether complex, heating to form 3-fluoroquinolines; intermediate for forming antibacterial compound | QRFPR, NQO2, DHX35 | CYP1A2 378/4885PDGFRB 3699/4885PDGFRA 2461/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | CYP1A2 2553/4885PDGFRB 4797/4885PDGFRA 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.