Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371336 | 0.82 | TAS2R38 (0.55) | SMN1; SMN2KDM4EHPGDHSD17B10ALDH1A1 | |
| Chelidamic Acid SCHEMBL742928 | 0.77 | ALOX15 (1.00) | ALOX15NFKB1BLMSMN1; SMN2KDM4E | |
| SCHEMBL308253 | 0.76 | KDM4E (0.69) | KDM4ECASP3SENP8SENP7SENP6 | |
| Chelidamic Acid SCHEMBL1176783 | 0.75 | ALOX15 (0.95) | ALOX15NFKB1BLMSMN1; SMN2KDM4E | |
| Chelidamic Acid SCHEMBL9658074 | 0.75 | ALOX15 (0.95) | ALOX15NFKB1BLMSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL6335114 | 0.75 | KDM4E (0.67) | SMN1; SMN2KDM4ECASP3SENP8SENP7 | |
| SCHEMBL316366 | 0.73 | KDM4E (0.47) | SMN1; SMN2KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL8341738 | 0.71 | KDM4E (0.67) | SMN1; SMN2KDM4ECASP3SENP8SENP7 | |
| SCHEMBL27699479 | 0.68 | KDM4E (0.53) | SMN1; SMN2KDM4ECASP3SENP8SENP7 | |
| SCHEMBL1259832 | 0.68 | HSD17B10 (0.47) | ALOX15NFKB1BLMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | ALOX15 2631/4885NFKB1 2131/4885BLM 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.