Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 11/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257512 | 0.81 | LMNA (0.48) | MEN1KMT2AFAAHL3MBTL1NPC1 | |
| SCHEMBL4257403 | 0.81 | TSHR (0.45) | GRM2MEN1KMT2A | |
| SCHEMBL4258569 | 0.77 | MMP1 (0.43) | GRM2MEN1KMT2AFAAHNPC1 | |
| SCHEMBL4265019 | 0.77 | KMT2A (0.42) | MEN1KMT2AFAAH | |
| SCHEMBL4271922 | 0.72 | GRM2 (0.38) | GRM2FAAH | |
| SCHEMBL4262167 | 0.72 | MAPT (0.43) | MEN1KMT2ANPC1 | |
| SCHEMBL4268039 | 0.71 | TACR2 (0.47) | KMT2AFAAH | |
| SCHEMBL4258709 | 0.71 | LMNA (0.46) | FAAH | |
| SCHEMBL4257406 | 0.71 | HDAC6 (0.43) | — | |
| SCHEMBL1086209 | 0.71 | GRM2 (0.42) | GRM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910381-B1 | SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]-DECAN-2-ON- COMPOUNDS AND THE USE THEREOF FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2009-06-03 | — | — | EP | disclosed |