Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273955 | 0.81 | ACHE (0.41) | KCNN4MAPTESR1ESR2HPGD | |
| SCHEMBL4272735 | 0.81 | CYP1A2 (0.38) | KCNN4CYP1A2MAPTALDH1A1HPGD | |
| SCHEMBL4266443 | 0.81 | CYP1A2 (0.38) | KCNN4CYP1A2MAPTALDH1A1HPGD | |
| SCHEMBL4270175 | 0.81 | CYP1A2 (0.38) | KCNN4CYP1A2MAPTALDH1A1HPGD | |
| SCHEMBL150540 | 0.76 | MAPT (0.43) | CYP1A2MAPTESR1ESR2ALDH1A1 | |
| SCHEMBL19858510 | 0.72 | ELANE (0.42) | MAPTESR1ESR2KDM4EGLA | |
| SCHEMBL9411498 | 0.72 | ELANE (0.45) | MAPTESR1ESR2ALDH1A1HPGD | |
| SCHEMBL9411666 | 0.70 | THRB (0.41) | MAPTESR1ESR2ALDH1A1HPGD | |
| SCHEMBL4268120 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL1086612 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |